The pursuit of perfection is frustrating and a waste of time, because nothing is ever perfect.
The pursuit of excellence is commendable and worthwhile. Therefore strive for excellence not perfection.
An arrogant person considers himself perfect. This is the chief harm of arrogance. It interferes with a person's main task in life—becoming a better person.
How can we say nobody's perfect if there is no perfect to compare to? Perfection implies that there really is a right and wrong way to be. And what type of perfection is the best type? Moral perfection? Aesthetic? Physiological? Mental?