Everybody kind of understands, Oh yeah you take drugs and it does something to your brain and then you can't stop. It's easier to describe that shame, that horrible feeling of not being able to control your own life.
When we think carefully, we see that the brief elation we experience when appeasing sensual impulses may not be very different from what the drug addict feels when indulging his or her habit. Temporary relief is soon followed by a craving for more. And in just the same way that taking drugs in the end only causes trouble, so, too, does much of what we undertake to fulfill our immediate sensory desires.
It isn't given to us to know those rare moments when people are wide open and the lightest touch can wither or heal. A moment too late and we can never reach them any more in this world. They will not be cured by our most efficacious drugs or slain with our sharpest swords.