It is one of the great weaknesses of reasonable men and women that they imagine that projects which fly in the face of commonsense are not serious or being seriously undertaken.
It will not be we who reach Alpha Centauri, and the other nearby stars. It will be a species very like us - but with more of our strengths and fewer of our weaknesses.
I think that everyone has something about themselves that they feel is their weakness... their 'disability.' And I'm certain we all have one, because I think of a disability as being anything which undermines our belief and confidence in our own abilities.