Although we deal with probabilities and expectations, the actual results can deviate substantially from such expectations, particularly on a short-term basis.
In my personal experience I have hardly come to know the wretchedness of mankind better than as a result of the general theory of relativity and everything connected to it. But it doesn't bother me.
German Nazism could not have succeeded in establishing itself except as a result of the theoretical contributions of Fichte, Goethe and Nietzsche, coupled with the ingenious and mighty leadership of Hitler and his comrades.