The true bounds and limitations, whereby human knowledge is confined and circumscribed,... are three: the first, that we do not so place our felicity in knowledge, as we forget our mortality: the second, that we make application of our knowledge, to give ourselves repose and contentment, and not distates or repining: the third, that we do not presume by the contemplation of Nature to attain to the mysteries of God.
There is another ground of hope that must not be omitted. Let men but think over their infinite expenditure of understanding, time, and means on matters and pursuits of far less use and value; whereof, if but a small part were directed to sound and solid studies, there is no difficulty that might not be overcome.
Human knowledge and human power meet in one; for where the cause is not known the effect cannot be produced. Nature to be commanded must be obeyed; and that which in contemplation is as the cause is in operation as the rule.
It cannot be that axioms established by argumentation should avail for the discovery of new works, since the subtlety of nature is greater many times over than the subtlety of argument. But axioms duly and orderly formed from particulars easily discover the way to new particulars, and thus render sciences active.