Remember the Three Princes of Serendip who went out looking for treasure? They didn't find what they were looking for, but they kept finding things just as valuable. That's serendipity, and our business [drugs] is full of it.
Descartes constructed as noble a road of science, from the point at which he found geometry to that to which he carried it, as Newton himself did after him. ... He carried this spirit of geometry and invention into optics, which under him became a completely new art.
Concern for man himself and his fate must always form the chief interest of all technical endeavors, concern for the great unsolved problems of the organization of labor and the distribution of goods-in order that the creations of our mind shall be a blessing and not a curse to mankind. Never forget this in the midst of your diagrams and equations.
Ere long intelligence-transmitted without wires-will throb through the earth like a pulse through a living organism. The wonder is that, with the present state of knowledge and the experiences gained, no attempt is being made to disturb the electrostatic or magnetic condition of the earth, and transmit, if nothing else, intelligence.
Of all the communities available to us, there is not one I would want to devote myself to except for the society of the true seekers, which has very few living members at any one time.
[Science] is not perfect. It can be misused. It is only a tool. But it is by far the best tool we have, self-correcting, ongoing, applicable to everything. It has two rules. First: there are no sacred truths; all assumptions must be critically examined; arguments from authority are worthless. Second: whatever is inconsistent with the facts must be discarded or revised. ... The obvious is sometimes false; the unexpected is sometimes true.
It may be that ... when the advance of destructive weapons enables everyone to kill everybody else nobody will want to kill anyone at all. [Referring to the hydrogen bomb.]
But what is classification but the perceiving that these objects are not chaotic, and are not foreign, but have a law which is also the law of the human mind?
Whether statistics be an art or a science... or a scientific art, we concern ourselves little. It is the basis of social and political dynamics, and affords the only secure ground on which the truth or falsehood of the theories and hypotheses of that complicated science can be brought to the test.
Thinking is seeing.... Every human science is based on deduction, which is a slow process of seeing by which we work up from the effect to the cause; or, in a wider sense, all poetry like every work of art proceeds from a swift vision of things.
Who are we? We find that we live on an insignificant planet of a humdrum star lost in a galaxy tucked away in some forgotten corner of a universe in which there are far more galaxies than people.
All science is methodolgy with regard to the Absolute. Therefore, there need be no fear of the unequivocally methodological. It isa husk, but not more than everything except the One.
It is idle to expect any great advancement in science from the superinducing and engrafting of new things upon old. We must begin anew from the very foundations, unless we would revolve for ever in a circle with mean and contemptible progress.
This world was once a fluid haze of light, Till toward the centre set the starry tides, And eddied into suns, that wheeling cast The planets: then the monster, then the man.
The mighty edifice of Government science dominated the scene in the middle of the 20th century as a Gothic cathedral dominated a 13th century landscape. The work of many hands over many years, it universally inspired admiration, wonder and fear.