We cannot step aside and say that we have achieved our goal by inventing a new drug or a new way by which to treat presently incurable diseases, a new way to help those who suffer from malnutrition, or the creation of ideal balanced diets on a worldwide scale. We cannot rest till the way has been found, with our help, to bring our finest achievement to everyone.
When we think how narrow and devious this path of nature is, how dimly we can trace it, for all our lamps of science, and how from the darkness which girds it round great and terrible possibilities loom ever shadowly upwards, it is a bold and a confident man who will put a limit to the strange by-oaths into which the human spirit may wander.
My parents were not scientists. They knew almost nothing about science. But in introducing me simultaneously to skepticism and to wonder, they taught me the two uneasily cohabiting modes of thought that are central to the scientific method.
When Newton saw an apple fall, he found In that slight startle from his contemplation- 'Tis said (for I'll not answer above ground For any sage's creed or calculation)- A mode of proving that the earth turn'd round In a most natural whirl, called 'gravitation'; And this is the sole mortal who could grapple, Since Adam, with a fall, or with an apple.
"The Universe repeats itself, with the possible exception of history." Of all earthly studies history is the only one that does not repeat itself. ... Astronomy repeats itself; botany repeats itself; trigonometry repeats itself; mechanics repeats itself; compound long division repeats itself. Every sum if worked out in the same way at any time will bring out the same answer. ... A great many moderns say that history is a science; if so it occupies a solitary and splendid elevation among the sciences; it is the only science the conclusions of which are always wrong.
Ere long intelligence-transmitted without wires-will throb through the earth like a pulse through a living organism. The wonder is that, with the present state of knowledge and the experiences gained, no attempt is being made to disturb the electrostatic or magnetic condition of the earth, and transmit, if nothing else, intelligence.
Remember the Three Princes of Serendip who went out looking for treasure? They didn't find what they were looking for, but they kept finding things just as valuable. That's serendipity, and our business [drugs] is full of it.
BRAIN, n. An apparatus with which we think that we think. That which distinguishes the man who is content to be something from the man who wishes to do something. A man of great wealth, or one who has been pitchforked into high station, has commonly such a headful of brain that his neighbors cannot keep their hats on. In our civilization, and under our republican form of government, brain is so highly honored that it is rewarded by exemption from the cares of office.
...we are all inclined to ... direct our inquiry not by the matter itself, but by the views of our opponents; and, even when interrogating oneself, one pushes the inquiry only to the point at which one can no longer offer any opposition. Hence a good inquirer will be one who is ready in bringing forward the objections proper to the genus, and that he will be when he has gained an understanding of the differences.
Who then understands the reciprocal flux and reflux of the infinitely great and the infinitely small, the echoing of causes in the abysses of being, and the avalanches of creation?
Therefore the moon, the governess of floods,
Pale in her anger washes all the air,
That rheumatic diseases do abound;
And through this distemperature we see
The seasons alter: hoary-headed frosts
Fall in the fresh lap of the crimson rose.