Edison was by far the most successful and, probably, the last exponent of the purely empirical method of investigation. Everything he achieved was the result of persistent trials and experiments often performed at random but always attesting extraordinary vigor and resource. Starting from a few known elements, he would make their combinations and permutations, tabulate them and run through the whole list, completing test after test with incredible rapidity until he obtained a clue. His mind was dominated by one idea, to leave no stone unturned, to exhaust every possibility.
The key to realizing a dream is to focus not on success but significance - and then even the small steps and little victories along your path will take on greater meaning.
The tree which needs two arms to span its girth sprang from the tiniest shoot. Yon tower, nine stories high, rose from a little mound of earth. A journey of a thousand miles begins with a single step.
Ambitious men spend their youth in rendering themselves worthy of patronage; it is their great mistake. While the foolish creatures are laying in stores of knowledge and energy, so that they shall not sink under the weight of responsible posts that recede from them, schemers come and go who are wealthy in words and destitute of ideas, astonish the ignorant, and creep into the confidence of those who have a little knowledge.