But I try not to think with my gut. If I'm serious about understanding the world, thinking with anything besides my brain, as tempting as that might be, is likely to get me into trouble.
There is another ground of hope that must not be omitted. Let men but think over their infinite expenditure of understanding, time, and means on matters and pursuits of far less use and value; whereof, if but a small part were directed to sound and solid studies, there is no difficulty that might not be overcome.
If you are out to describe the truth, leave elegance to the tailor.
On being reproached that his formula of gravitation was longer and more cumbersome than Newton's.
If a man will comprehend the richness and variety of the universe, and inspire his mind with a due measure of wonder and awe, he must contemplate the human intellect not only on its heights of genius but in its abysses of ineptitude.
Do you believe then that the sciences would ever have arisen and become great if there had not before hand been magicians, alchemists, astrologers and wizards, who thirsted and hungered after abscondite and forbidden powers?
We live in a society exquisitely dependent on science and technology and yet have cleverly arranged things so that almost no one understands science and technology.
As agonizing a disease as cancer is, I do not think it can be said that our civilization is threatened by it. ... But a very plausible case can be made that our civilization is fundamentally threatened by the lack of adequate fertility control. Exponential increases of population will dominate any arithmetic increases, even those brought about by heroic technological initiatives, in the availability of food and resources, as Malthus long ago realized.
Neither the naked hand nor the understanding left to itself can effect much. It is by instruments and helps that the work is done, which are as much wanted for the understanding as for the hand. And as the instruments of the hand either give motion or guide it, so the instruments of the mind supply either suggestions for the understanding or cautions.
Remember the Three Princes of Serendip who went out looking for treasure? They didn't find what they were looking for, but they kept finding things just as valuable. That's serendipity, and our business [drugs] is full of it.