Some authors have conceptualized depression as a "depletion syndrome" because of the prominence of fatigability; they postulate that the patient exhausts his available energy during the period prior to the onset of the depression and that the depressed state represents a kind of hibernation, during which the patient gradually builds up a new story of energy.
Why is it that all those who have become eminent in philosophy, politics, poetry, or the arts are clearly of an atrabilious temperament and some of them to such an extent as to be affected by diseases caused by black bile?
Imagine a society that subjects people to conditions that make them terribly unhappy, then gives them the drugs to take away their unhappiness. Science fiction? It is already happening to some extent in our own society... Instead of removing the conditions that make people depressed, modern society gives them antidepressant drugs. In effect, antidepressants are a means of modifying an individual's internal state in such a way as to enable him to tolerate social conditions that he would otherwise find intolerable.
... he preferred his own madness, to the regular sanity. He rejoiced in his own madness, he was free. He did not want that old sanity of the world, which was become so repulsive. He rejoiced in the new-found world of his madness. It was so fresh and delicate and so satisfying.
You can hold yourself back from the sufferings of the world, that is something you are free to do and it accords with your nature, but perhaps this very holding back is the one suffering you could avoid.
Every act of life, from the morning toothbrush to the friend at dinner, became an effort. I hated the night when I couldn't sleep and I hated the day because it went toward night.
You shall be free indeed when your days are not without a care, nor your nights without a want and a grief, but rather when these things girdle your life and yet you rise above them naked and unbound.
Each sporadic burst of work, each minor success and disappointment, each moment of calm and relaxation, seemed merely a temporary halt on my steady descent through layer after layer of depression, like an elevator stopping for a moment on the way down to the basement.