Antidepressants are very good, but it's a clinical cosh, really. Sometimes you have to be knocked out, just to stop; when you're in that state all you want to do is just sleep, and rest your body and your brain.
My fundamental premise about the brain is that its workings - what we sometimes call "mind" - are a consequence of its anatomy and physiology, and nothing more.
If you desire to be pure, have firm faith, and slowly go on with your devotional practices without wasting your energy in useless scriptural discussions and arguments. Your little brain will otherwise be muddled.
Art bids us touch and taste and hear and see the world, and shrinks from what Blake calls mathematic form, from every abstract form, from all that is of the brain only.