I understood that you would take the Human Race in the concrete, have exploded the absurd notion of Pope's Essay on Man, [Erasmus] Darwin, and all the countless Believers-even (strange to say) among Xtians-of Man's having progressed from an Ouran Outang state-so contrary to all History, to all Religion, nay, to all Possibility-to have affirmed a Fall in some sense.
Our world faces a crisis as yet unperceived by those possessing power to make great decisions for good or evil. The unleashed power of the atom has changed everything save our modes of thinking and we thus drift toward unparalleled catastrophe.
Next you'd see a raft sliding by, away off yonder, and maybe a galoot on it chopping. . . you'd see the ax flash and come down-you don't hear nothing; you see the ax go up again, and by the time it's above the man's head then you hear the k'chunk!-it had took all that time to come over the water.
The End of our Foundation is the knowledge of Causes; and secret motions of things; and the enlarging of the bounds of Human Empire, to the effecting of all things possible.
Nevertheless if any skillful Servant of Nature shall bring force to bear on matter, and shall vex it and drive it to extremities as if with the purpose of reducing it to nothing, then will matter (since annihilation or true destruction is not possible except by the omnipotence of God) finding itself in these straits, turn and transform itself into strange shapes, passing from one change to another till it has gone through the whole circle and finished the period.
[N]o scientist likes to be criticized. ... But you don't reply to critics: "Wait a minute, wait a minute; this is a really good idea. I'm very fond of it. It's done you no harm. Please don't attack it." That's not the way it goes. The hard but just rule is that if the ideas don't work, you must throw them away. Don't waste any neurons on what doesn't work. Devote those neurons to new ideas that better explain the data. Valid criticism is doing you a favor.
The secrets of evolution are death and time-the deaths of enormous numbers of lifeforms that were imperfectly adapted to the environment; and time for a long succession of small mutations.
The lessons of science should be experimental also. The sight of a planet through a telescope is worth all the course on astronomy; the shock of the electric spark in the elbow outvalues all theories; the taste of the nitrous oxide, the firing of an artificial volcano, are better than volumes of chemistry.