All science is methodolgy with regard to the Absolute. Therefore, there need be no fear of the unequivocally methodological. It isa husk, but not more than everything except the One.
A prince must be prudent enough to know how to escape the bad reputation of those vices that would lose the state for him, and must protect himself from those that will not lose it for him, if this is possible; but if he cannot, he need not concern himself unduly if he ignores these less serious vices.
Certainly we do not need quantum mechanics for macroscopic objects, which are well described by classical physics - this is the reason why quantum mechanics seems so foreign to our everyday existence.
You've got to do the big studio movies to get your name, but as an actor and for your own well-being you kind of need to step back from that occasionally and do the smaller films. In the end, that's what helps you learn and makes you a better actor.
When we have become free, we need not go mad and throw up society and rush off to die in the forest or the cave; we shall remain where we were but we shall understand the whole thing. The same phenomena will remain but with a new meaning.